| designer | creator |
| desinare | dinner |
| desinfezione | fumigation |
| Desiré-Félicien-François-Joseph Mercier | Désiré-Joseph Mercier |
| desistere | relinquish |
| Desktop | Desk |
| Desktop environment | Desk |
| Desktop search | Desktop search |
| Desmond Connell | Desmond Connell |
| Desmond Hume | Desmond Hume |
| Desmond Llewelyn | Desmond Llewelyn |
| Desmond Tutu | Desmond Tutu |
| Desmonts | Demon |
| Desmosina | Desmosine |
| Desna | Desna River |
| desolante | distressing |
| desolare | ravage |
| desolato | stark |
| desolforazione | desulphurisation |
| desolforazione dei combustibili | desulphurisation of fuel |
| Desperate Housewives | Desperate Housewives |
| Despina | Despina |
| despota | despot |
| Despotato di Morea | Despotate of Morea |
| despotismo | tyranny |
| Despotovac | Despotovac |
| Dessau | Dessau |
| dessert | dessert |
| destabilizzazione | destabilization |
| destare | arouse |
| destare l'interesse di | fascinate |
| Destare scalpore | Bang about |
| destarsi | rouse |
| destinare | mean |
| destinare a | refer to |
| destinataria | addressee |
| destinatario | addressee |
